Compile Data Set for Download or QSAR

Found 4 hits of Enzyme Inhibition Constant Data   

TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
* indicates data uncertainty>20%