Compile Data Set for Download or QSAR

Found 6 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443181(CHEMBL3086535)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443180(CHEMBL3086536)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443175(CHEMBL3086534)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443181(CHEMBL3086535)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443180(CHEMBL3086536)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443175(CHEMBL3086534)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
* indicates data uncertainty>20%