Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075302((3-ethynylphenyl)(difluoro)methylphosphonate | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075306(CHEMBL151494 | {3-[bis(methylsulfonyl)amino]-4-[(E...)copy SMILEScopy InChI
Affinity DataIC50: 5.79E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075313(CHEMBL150915 | [(4-Ethynyl-phenyl)-difluoro-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 7.75E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075310(CHEMBL357094 | [3-[bis(methylsulfonyl)amino]-4-(ph...)copy SMILEScopy InChI
Affinity DataIC50: 8.87E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075305(CHEMBL149279 | [Difluoro-(4-phenylethynyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075309(CHEMBL150420 | [Difluoro-(3-phenylethynyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075303(CHEMBL150349 | [Difluoro-(3-methanesulfonylamino-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075311(CHEMBL150350 | [Difluoro-(3-methanesulfonylamino-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075314(CHEMBL151300 | difluoro{3-[(E)-2-phenylvinyl]pheny...)copy SMILEScopy InChI
Affinity DataIC50: 3.86E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075304(CHEMBL150295 | {Difluoro-[4-((E)-styryl)-phenyl]-m...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075307(CHEMBL150202 | [Difluoro-(4'-methoxy-biphenyl-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.51E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 7.18E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075308((Biphenyl-4-yl-difluoro-methyl)-phosphonic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 7.79E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed
* indicates data uncertainty>20%