Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084141((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | CHEMBL88553 | NSC_5218788 | SIB-1757)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084139(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084141((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | CHEMBL88553 | NSC_5218788 | SIB-1757)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084136((R)-1-Amino-indan-1,5-dicarboxylic acid | CHEMBL35...)copy SMILEScopy InChI
Affinity DataIC50: 2.14E+5nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084136((R)-1-Amino-indan-1,5-dicarboxylic acid | CHEMBL35...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084139(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)copy SMILEScopy InChI
Affinity DataEC50:  1.03E+5nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50084142(Amino-(2-chloro-5-hydroxy-phenyl)-acetic acid | CH...)copy SMILEScopy InChI
Affinity DataEC50:  7.50E+5nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Universit¿a di Perugia

Curated by ChEMBL
LigandPNGBDBM50079183((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid | (S)...)copy SMILEScopy InChI
Affinity DataEC50:  6.60E+3nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6RGSPubMed
* indicates data uncertainty>20%