Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101077((1S,4S)-2-((S)-2-{(S)-2-[2-Amino-3-(4-phosphonooxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101077((1S,4S)-2-((S)-2-{(S)-2-[2-Amino-3-(4-phosphonooxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of trypsin in human mast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101081((S)-4-((S)-2-{2-Acetylamino-3-[4-(2-methoxycarbony...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of trypsin in human mast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101078((S)-4-{2-Acetylamino-3-[4-(2-methoxycarbonyl-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of trypsin in human mast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101079(4-((S)-1-Carbamoyl-2-methyl-butylcarbamoyl)-4-((S)...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101083((S)-4-((1S,2S)-1-Carbamoyl-2-methyl-butylcarbamoyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of trypsin in human mast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101080(2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101082(3-(2-{(S)-1-[(S)-1-((S)-(S)-1-Carbamoyl-2-methyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101079(4-((S)-1-Carbamoyl-2-methyl-butylcarbamoyl)-4-((S)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of trypsin in human mast cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101081((S)-4-((S)-2-{2-Acetylamino-3-[4-(2-methoxycarbony...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101080(2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101078((S)-4-{2-Acetylamino-3-[4-(2-methoxycarbonyl-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50101083((S)-4-((1S,2S)-1-Carbamoyl-2-methyl-butylcarbamoyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3C8BPubMed
* indicates data uncertainty>20%