Compile Data Set for Download or QSAR

Found 20 hits of Enzyme Inhibition Constant Data   

TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102059((3R,4R)-3-[2-(5-Bromo-2-chloro-phenyl)-ethyl]-4-fl...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102064(3-[2-(5-Bromo-2-chloro-phenyl)-vinyl]-piperidine; ...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102057(3-[2-(5-Bromo-2-chloro-phenyl)-ethyl]-piperidine; ...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102061(3-[2-(2,5-Dichloro-phenyl)-ethyl]-piperidine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102051(3-[2-(3,4-Dichloro-phenyl)-ethyl]-piperidine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102060(3-[2-(2,6-Dichloro-phenyl)-ethyl]-piperidine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102056(3-[2-(3,5-Bis-trifluoromethyl-phenyl)-ethyl]-piper...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102067((3S,4S)-3-[3-(5-Bromo-2-chloro-phenyl)-propyl]-4-f...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102052(5-(5-bromo-2-chlorobenzyl)-4-fluoro-1,2,3,6-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102049(5-(5-Bromo-2-chloro-benzyl)-1,2,3,6-tetrahydro-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102053((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-5-guan...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102050((S)-3-(5-Bromo-2-chloro-benzyl)-piperidin-4-ol; hy...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102058((3S,4S)-3-(5-Bromo-2-chloro-benzyl)-piperidin-4-ol...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102065(3-[2-(3-Chloro-2'-methoxy-biphenyl-4-yl)-ethyl]-pi...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102066((3S,4S)-3-(5-Bromo-2-chloro-benzyl)-4-fluoro-piper...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102068(3-Phenethyl-piperidine | CHEMBL55554)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102062(3-(5-Bromo-2-chloro-benzyl)-piperidin-4-one; hydro...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102063(3-[2-(4-Ethoxy-phenyl)-ethyl]-piperidine | CHEMBL5...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102055(4-(2-Piperidin-3-yl-ethyl)-benzonitrile | CHEMBL55...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Escherichia coli (strain K12))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50102054(3-[2-(2,5-Dimethyl-phenyl)-ethyl]-piperidine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibitory activity against accumulation of [14C]-labeled Linezolid within wild-type Escherichia coli K12 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251JPXPubMed
* indicates data uncertainty>20%