Compile Data Set for Download or QSAR

Found 32 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103784(CHEMBL77638 | Phosphoric acid mono-(4-{2-acetylami...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103784(CHEMBL77638 | Phosphoric acid mono-(4-{2-acetylami...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103780(CHEMBL308734 | [4-{2-Acetylamino-2-[(S)-1-(3-carba...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)copy SMILEScopy InChI
Affinity DataIC50: 9.45E+4nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103780(CHEMBL308734 | [4-{2-Acetylamino-2-[(S)-1-(3-carba...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.03E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103787((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103785(CHEMBL263721 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 3.78E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103784(CHEMBL77638 | Phosphoric acid mono-(4-{2-acetylami...)copy SMILEScopy InChI
Affinity DataIC50: 4.41E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103780(CHEMBL308734 | [4-{2-Acetylamino-2-[(S)-1-(3-carba...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103778(CHEMBL311114 | [5-{2-[1-(3-Carbamoyl-4-cyclohexylm...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103779(CHEMBL430825 | Trifluoro-methanesulfonic acid 4-{2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103783(CHEMBL308164 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103779(CHEMBL430825 | Trifluoro-methanesulfonic acid 4-{2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103779(CHEMBL430825 | Trifluoro-methanesulfonic acid 4-{2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103778(CHEMBL311114 | [5-{2-[1-(3-Carbamoyl-4-cyclohexylm...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103785(CHEMBL263721 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103785(CHEMBL263721 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103787((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103778(CHEMBL311114 | [5-{2-[1-(3-Carbamoyl-4-cyclohexylm...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103783(CHEMBL308164 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50103783(CHEMBL308164 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513XHJPubMed
* indicates data uncertainty>20%