Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106995(1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-pyrrolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106991(5-Pyridin-2-yl-thiophene-2-sulfonic acid methyl-{2...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106996(CHEMBL105987 | Thiophene-2-sulfonic acid methyl-{2...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106993(5-Pyridin-2-yl-thiophene-2-sulfonic acid {4-[4-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106997(1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-pyrrolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106994(CHEMBL421598 | Thiophene-2-sulfonic acid {4-[4-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106998(4-(3-Phenyl-propyl)-1-[4-phenyl-1-(thiophene-2-sul...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106992(4-(3-Phenyl-propyl)-1-[(3S,4S)-4-phenyl-1-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096557(CHEMBL312701 | N-[(S)-2-(3-Chloro-phenyl)-4-(4-phe...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106990(4-(3-Phenyl-propyl)-1-[(3S,4S)-4-phenyl-1-(5-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106999(2-(5-{(3S,4S)-3-Phenyl-4-[4-(3-phenyl-propyl)-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105518(CHEMBL327846 | Phenyl-[(3S,4S)-3-phenyl-4-(4-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Ability to inhibit binding of [125I]-MIP-1 alpha to C-C chemokine receptor type 5 in Chinese hamster ovary (CHO) cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4J4WPubMed
* indicates data uncertainty>20%