Affinity Data by PubMed id=11750180

Found 139 hits of Enzyme Inhibition Constant Data

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 0.5nMMore data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Norepinephrine transporter(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 3.60nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 7.5nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed DrugBank

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 82nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed DrugBank

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 138nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 240nMMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed DrugBank

5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 419nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 504nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 916nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Alpha-2B adrenergic receptor(MOUSE)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Voltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Muscarinic acetylcholine receptor M1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Muscarinic acetylcholine receptor M2(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Glutamate receptor ionotropic, NMDA 1(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Glutamate receptor ionotropic, NMDA 1(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

5'-nucleotidase(Rattus norvegicus (Rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Calcium-activated potassium channel subunit beta-1(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Protein kinase C alpha type(MOUSE)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sodium channel protein type 1 subunit alpha(Rattus norvegicus)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

5-hydroxytryptamine receptor 4(GUINEA PIG)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sodium/nucleoside cotransporter(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Voltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Gastrin/cholecystokinin type B receptor(MOUSE)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Gamma-aminobutyric acid receptor subunit alpha-1(BOVINE)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Gamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Glutamate receptor ionotropic, NMDA 1(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Histamine H2 receptor(Cavia porcellus (domestic guinea pig))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Histamine H2 receptor(Cavia porcellus (domestic guinea pig))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Substance-P receptor(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Alpha-bungarotoxin(Bungarus multicinctus)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Nitric oxide synthase, brain(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Mu-type opioid receptor(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

5-hydroxytryptamine receptor 4(GUINEA PIG)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Adenosine receptor A1(Rattus norvegicus (rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Adenosine receptor A2b(BOVINE)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Adenylate cyclase type 3(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Beta-1 adrenergic receptor(Rattus norvegicus (Rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

D(1A) dopamine receptor(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Neuromedin-K receptor(mouse)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Sodium/nucleoside cotransporter(RAT)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Alpha-2A adrenergic receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Alpha-2A adrenergic receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Beta-1 adrenergic receptor(Rattus norvegicus (Rat))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Beta-2 adrenergic receptor(Rattus norvegicus)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB MMDB
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Muscarinic acetylcholine receptor M2(Homo sapiens (Human))
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

PDB
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BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Gamma-aminobutyric acid receptor subunit alpha-1(BOVINE)
Lilly Research Laboratories

Curated by PDSP K_i Database

BDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI

Ki: 1.00E+3nMMore data for this Ligand-Target Pair

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Details Article
BindingDB Entry DOI: 10.7270/Q25M648WPubMed

Displayed 1 to 50 (of 139 total ) | Next | Last >>* indicates data uncertainty>20%

Targets 59 ▿
- Gamma-aminobutyric acid receptor subunit alpha-1 6
- Gastrin/cholecystokinin type B receptor 4
- Alpha-1A adrenergic receptor 4
- Sigma non-opioid intracellular receptor 1 4
- Glutamate receptor ionotropic, NMDA 1 4
- Muscarinic acetylcholine receptor M2 4
- Mu-type opioid receptor 4
- Alpha-2A adrenergic receptor 4
- Glycine receptor subunit alpha-1 4
- Sodium-dependent serotonin transporter 3
- Sodium-dependent noradrenaline transporter 2
- 5'-nucleotidase 2
- Muscarinic acetylcholine receptor M1 2
- Beta-2 adrenergic receptor 2
- Beta-1 adrenergic receptor 2
- D(2) dopamine receptor 2
- Delta-type opioid receptor 2
- Voltage-dependent N-type calcium channel subunit alpha-1B 2
- Sodium/nucleoside cotransporter 2
- Norepinephrine transporter 2
- Sodium-dependent dopamine transporter 2
- Alpha-bungarotoxin 2
- Glutamate receptor 3 2
- ATP-sensitive inward rectifier potassium channel 1 2
- 5-hydroxytryptamine receptor 2C 2
- 5-hydroxytryptamine receptor 2B 2
- 5-hydroxytryptamine receptor 2A 2
- D(1A) dopamine receptor 2
- 5-hydroxytryptamine receptor 4 2
- Adenylate cyclase type 3 2
- 5-hydroxytryptamine receptor 7 2
- 5-hydroxytryptamine receptor 6 2
- Sodium channel protein type 1 subunit alpha 2
- Sodium channel protein type 2 subunit alpha 2
- Substance-K receptor 2
- Adenosine receptor A1 2
- Kappa-type opioid receptor 2
- Histamine H1 receptor 2
- 5-hydroxytryptamine receptor 1B 2
- 5-hydroxytryptamine receptor 1A 2
- Somatostatin 2
- 5-hydroxytryptamine receptor 1F 2
- Voltage-dependent L-type calcium channel subunit alpha-1C 2
- 5-hydroxytryptamine receptor 1E 2
- 5-hydroxytryptamine receptor 1D 2
- Amine oxidase [flavin-containing] B 2
- Substance-P receptor 2
- Amine oxidase [flavin-containing] A 2
- Alpha-2B adrenergic receptor 2
- Protein kinase C alpha type 2
- Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 2
- Neuropeptide Y receptor type 1 2
- Neuromedin-K receptor 2
- Alpha-1B adrenergic receptor 2
- Nitric oxide synthase, brain 2
- Glutamate receptor ionotropic, kainate 1 2
- Calcium-activated potassium channel subunit beta-1 2
- Adenosine receptor A2b 2
- Histamine H2 receptor 2
Publications 1 ▿
- Neuropsychopharmacology 25: 871-80 (2001) 139
Institutions 1 ▿
- [Lilly Research Laboratories] 139
Affinity: 0.5 to 1.0E+4 nM▿
- Ki 139
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 2