Compile Data Set for Download or QSAR

Found 43 hits of Enzyme Inhibition Constant Data   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108192(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108194(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-4-sulf...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108187(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108185(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108196(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108188(CHEMBL279947 | N-[2-Benzo[1,3]dioxol-5-yl-2-(6-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50451439(CHEMBL2114305)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108198(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108190(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108207(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108187(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108205(CHEMBL281378 | N-{2-Benzo[1,3]dioxol-5-yl-2-[1-met...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108199(CHEMBL279703 | N-[2-(6-Aminomethyl-1-methyl-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108201(CHEMBL274758 | N-[2-Benzo[1,3]dioxol-5-yl-2-(6-cya...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108196(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108189(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108185(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108206(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108199(CHEMBL279703 | N-[2-(6-Aminomethyl-1-methyl-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 204nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108186(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108198(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108195(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 228nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108192(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 302nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108191(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)copy SMILEScopy InChI
Affinity DataIC50: 397nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108188(CHEMBL279947 | N-[2-Benzo[1,3]dioxol-5-yl-2-(6-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108189(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 474nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108194(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-4-sulf...)copy SMILEScopy InChI
Affinity DataIC50: 774nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108193(2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 846nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108203(3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulf...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108200(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulf...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50451439(CHEMBL2114305)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108207(3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50108197(3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+3nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]-ET-1 displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KG6PubMed
* indicates data uncertainty>20%