Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM6477(4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4531(4-Phenylamino-3-quinolinecarbonitrile deriv. 1i | ...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095226(6,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Dual specificity mitogen-activated protein kinase kinase (MEK-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109282(7,8-Dimethoxy-4-(4-phenoxy-phenylamino)-benzo[g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Dual specificity mitogen-activated protein kinase kinase (MEK-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109281(4-(2,4-Dichloro-phenylamino)-7,8-dimethoxy-benzo[g...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4492(4-[(2,4-Dichlorophenyl)amino]-6,7-dimethoxy-3-quin...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM6477(4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of Src-transformed fibroblast cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4456(4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4531(4-Phenylamino-3-quinolinecarbonitrile deriv. 1i | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4456(4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)copy SMILEScopy InChI
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1CQ7PubMed
* indicates data uncertainty>20%