Compile Data Set for Download or QSAR

Found 59 hits of Enzyme Inhibition Constant Data   

TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109783(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109790(5-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109789(2-(4-Dimethylamino-phenyl)-3-[2-(4-pyrimidin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109793(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109800(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109793(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109788(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109786(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109809(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109809(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109787(2-Biphenyl-4-yl-3-[2-(6,7-dimethoxy-3,4-dihydro-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109786(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109800(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109787(2-Biphenyl-4-yl-3-[2-(6,7-dimethoxy-3,4-dihydro-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109796(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109797(8-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109796(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109806(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109810(2-(4-Diethylamino-phenyl)-3-[2-(6,7-dimethoxy-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109805(7-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109805(7-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109802(2-Benzo[1,3]dioxol-5-yl-3-[2-(6,7-dimethoxy-3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109782(6-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109785(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109782(6-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109794(3-(2-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-methyl-amin...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109798(6-Amino-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquin...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109806(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109804(3-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-2-(4-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109795(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109797(8-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109808(3-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-ethyl]-2-(4...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109807(2-(4-Dimethylamino-phenyl)-3-(2-pyridin-4-yl-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109802(2-Benzo[1,3]dioxol-5-yl-3-[2-(6,7-dimethoxy-3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109790(5-Chloro-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoqui...)copy SMILEScopy InChI
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109784(2-(4-Dimethylamino-phenyl)-3-{2-[4-(3,4,5-trimetho...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109785(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109808(3-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-ethyl]-2-(4...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109811((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-acetyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109788(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109784(2-(4-Dimethylamino-phenyl)-3-{2-[4-(3,4,5-trimetho...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109801(7-Amino-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquin...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109798(6-Amino-3-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquin...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109795(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109799(3-Cyclohexylmethyl-2-(4-dimethylamino-phenyl)-3H-q...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109807(2-(4-Dimethylamino-phenyl)-3-(2-pyridin-4-yl-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109810(2-(4-Diethylamino-phenyl)-3-[2-(6,7-dimethoxy-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109799(3-Cyclohexylmethyl-2-(4-dimethylamino-phenyl)-3H-q...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against P-glyco-protein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Xenova Ltd.

Curated by ChEMBL
LigandPNGBDBM50109783(3-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6JP9PubMed
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