Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111900(4-[4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111901(2-(5-(4-methylpiperazin-1-ylsulfonyl)-2-propoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111898(2-(2-Propoxy-phenyl)-9-propyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
LigandPNGBDBM50111900(4-[4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111900(4-[4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111898(2-(2-Propoxy-phenyl)-9-propyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111901(2-(5-(4-methylpiperazin-1-ylsulfonyl)-2-propoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111898(2-(2-Propoxy-phenyl)-9-propyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111900(4-[4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111901(2-(5-(4-methylpiperazin-1-ylsulfonyl)-2-propoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
BAYER AG

Curated by ChEMBL
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5D80PubMed
* indicates data uncertainty>20%