Compile Data Set for Download or QSAR

Found 63 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 12.5nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8806((1R,2R)-N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8806((1R,2R)-N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8805(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8794(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8795(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-[4-(phe...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8794(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8808(3-{4-[(1H-indol-2-ylmethyl)amino]phenyl}-1-[4-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8802(3-[4-(benzylamino)-3-methoxyphenyl]-1-[4-(4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8795(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-[4-(phe...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8802(3-[4-(benzylamino)-3-methoxyphenyl]-1-[4-(4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8804(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 92nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 93nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8796(3-(4-benzoylphenyl)-1-[4-(4-methylpiperazin-1-yl)c...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8805(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8800(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 155nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8801(Pyrazolo[3,4-d]pyrimidine 9 | [(4-{4-amino-1-[4-(4...)copy SMILEScopy InChI
Affinity DataIC50: 167nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 189nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8808(3-{4-[(1H-indol-2-ylmethyl)amino]phenyl}-1-[4-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 203nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8799(3-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 209nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8799(3-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 263nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8806((1R,2R)-N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 275nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8799(3-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8796(3-(4-benzoylphenyl)-1-[4-(4-methylpiperazin-1-yl)c...)copy SMILEScopy InChI
Affinity DataIC50: 427nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8808(3-{4-[(1H-indol-2-ylmethyl)amino]phenyl}-1-[4-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 435nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8804(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8801(Pyrazolo[3,4-d]pyrimidine 9 | [(4-{4-amino-1-[4-(4...)copy SMILEScopy InChI
Affinity DataIC50: 463nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 521nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8808(3-{4-[(1H-indol-2-ylmethyl)amino]phenyl}-1-[4-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 526nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8795(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-[4-(phe...)copy SMILEScopy InChI
Affinity DataIC50: 606nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8794(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8801(Pyrazolo[3,4-d]pyrimidine 9 | [(4-{4-amino-1-[4-(4...)copy SMILEScopy InChI
Affinity DataIC50: 888nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8805(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8799(3-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 933nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8802(3-[4-(benzylamino)-3-methoxyphenyl]-1-[4-(4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8804(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8800(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8795(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-[4-(phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.81E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154F84PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

LigandPNGBDBM8800(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 3.91E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2154F84PubMed
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