Compile Data Set for Download or QSAR

Found 15 hits of Enzyme Inhibition Constant Data   

TargetSubstance-P receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50279775((S)-3-Cyano-naphthalene-1-carboxylic acid {2-(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Inhibition of binding of [3H]SP to Tachykinin receptor 1 of human tachykinin receptor expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118098((S)-3-Cyano-naphthalene-1-carboxylic acid {2-(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibition of binding of [3H]SP to Tachykinin receptor 1 of human tachykinin receptor expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118100(3-Cyano-2-methoxy-naphthalene-1-carboxylic acid ((...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Inhibition of binding of [3H]SP to Tachykinin receptor 1 of human tachykinin receptor expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118099(1'-[4-[(3-Cyano-2-methoxy-naphthalene-1-carbonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibition of binding of [3H]SP to Tachykinin receptor 1 of human tachykinin receptor expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118098((S)-3-Cyano-naphthalene-1-carboxylic acid {2-(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  0.340nMAssay Description:Inhibition of binding of [3H]NKA to human Tachykinin receptor 2 (NK2) in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50279775((S)-3-Cyano-naphthalene-1-carboxylic acid {2-(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  0.640nMAssay Description:Inhibition of binding of [3H]NKA to human Tachykinin receptor 2 (NK2) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50409575(CHEMBL339767 | ZD-7944)copy SMILEScopy InChI
Affinity DataKi:  0.920nMAssay Description:Inhibition of binding of [3H]NKA to human Tachykinin receptor 2 (NK2) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118099(1'-[4-[(3-Cyano-2-methoxy-naphthalene-1-carbonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  9.40nMAssay Description:Inhibition of binding of [125I]MPNI to human Tachykinin receptor 3 (NK3) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118099(1'-[4-[(3-Cyano-2-methoxy-naphthalene-1-carbonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Inhibition of binding of [3H]NKA to human Tachykinin receptor 2 (NK2) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118098((S)-3-Cyano-naphthalene-1-carboxylic acid {2-(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Inhibition of binding of [125I]MPNI to human Tachykinin receptor 3 (NK3) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118100(3-Cyano-2-methoxy-naphthalene-1-carboxylic acid ((...)copy SMILEScopy InChI
Affinity DataKi:  67nMAssay Description:Inhibition of binding of [3H]NKA to human Tachykinin receptor 2 (NK2) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50279775((S)-3-Cyano-naphthalene-1-carboxylic acid {2-(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  74nMAssay Description:Inhibition of binding of [125I]MPNI to human Tachykinin receptor 3 (NK3) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50118100(3-Cyano-2-methoxy-naphthalene-1-carboxylic acid ((...)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Inhibition of binding of [125I]MPNI to human Tachykinin receptor 3 (NK3) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50409575(CHEMBL339767 | ZD-7944)copy SMILEScopy InChI
Affinity DataKi:  1.62E+3nMAssay Description:Inhibition of binding of [3H]SP to human Tachykinin receptor 1 expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals LP

Curated by ChEMBL
LigandPNGBDBM50409575(CHEMBL339767 | ZD-7944)copy SMILEScopy InChI
Affinity DataKi:  9.19E+3nMAssay Description:Inhibition of binding of [125I]MPNI to human Tachykinin receptor 3 (NK3) expressed in mouse erythroleukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862H6TPubMed
* indicates data uncertainty>20%