Compile Data Set for Download or QSAR

Found 23 hits of Enzyme Inhibition Constant Data   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119113(1-{3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyan...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119128(CHEMBL98265 | {3-[N'-(3-Methoxy-4-oxazol-5-yl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The compound was tested for it's in vitro inhibitor potency against inosine monophosphate dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119120(CHEMBL101941 | N-Butyl-3-[N'-(3-methoxy-4-oxazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119127(1-{3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyan...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119119(CHEMBL98740 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119130(CHEMBL60730 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119126(CHEMBL99625 | N''-cyano-N-[3-(hydroxymethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119115(CHEMBL101822 | N''-cyano-N-[3-methoxy-4-(1,3-oxazo...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119114(CHEMBL98393 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119124(CHEMBL101463 | {3-[N'-(3-Methoxy-4-oxazol-5-yl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119121(CHEMBL98322 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119110(CHEMBL99278 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119111(CHEMBL98904 | N''-methoxy-N-[3-methoxy-4-(1,3-oxaz...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119129(CHEMBL317497 | ethyl(1E)-[(3-methoxy-4-oxazole-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119123(CHEMBL329714 | N-Benzoyl-N'-(3-methoxy-4-oxazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119118(CHEMBL98225 | N-Acetyl-N'-(3-methoxy-4-oxazol-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119125(CHEMBL98500 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119112(CHEMBL98700 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119122(CHEMBL316946 | N''-cyano-N-[3-methoxy-4-(1,3-oxazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119116(CHEMBL318413 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119117(CHEMBL98215 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:The compound was tested for it's in vitro inhibitor potency against inosine monophosphate dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB454KPubMed
* indicates data uncertainty>20%