Compile Data Set for Download or QSAR

Found 15 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119321(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119316(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50106995(1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-pyrrolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119317(5-(4-{3-[1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-py...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105543(Allyl-{1-[(3S,4S)-1-(2-chloro-benzoyl)-4-phenyl-py...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119326(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119323(3-(4-{3-[1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119318(3-(3-(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyr...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119325((4-{3-[1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119327((3-{3-[1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119328(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119324(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119320(4-(3-(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119322(1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119319(2-(3-(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyr...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73ZBPubMed
* indicates data uncertainty>20%