Compile Data Set for Download or QSAR

Found 68 hits of Enzyme Inhibition Constant Data   

TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124419(CHEMBL172297 | Thiophene-2-sulfonic acid {3-[6-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124442(CHEMBL276949 | Thiophene-2-sulfonic acid {3-[6-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124449(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124446(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124443(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124444(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124419(CHEMBL172297 | Thiophene-2-sulfonic acid {3-[6-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124420(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124429(CHEMBL172030 | Thiophene-2-sulfonic acid {2-[6-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124432(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124431(5-Isopropyl-pyridine-2-sulfonic acid [6-(2-ethanes...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124446(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124418(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124439(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124438(4-tert-Butyl-N-[2-cyclopropyl-6-(3-ethanesulfonyla...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124427(5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124438(4-tert-Butyl-N-[2-cyclopropyl-6-(3-ethanesulfonyla...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124428(5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124448(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124429(CHEMBL172030 | Thiophene-2-sulfonic acid {2-[6-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124432(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124440(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124421(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124420(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124440(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124442(CHEMBL276949 | Thiophene-2-sulfonic acid {3-[6-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124451(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124434(4-tert-Butyl-N-[6-(3-ethanesulfonylamino-propoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124441(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124427(5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124439(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124430(4-tert-Butyl-N-[2-cyclopropyl-6-(2-ethanesulfonyla...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124431(5-Isopropyl-pyridine-2-sulfonic acid [6-(2-ethanes...)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124441(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124445(5-Methyl-pyridine-2-sulfonic acid [6-(2-ethanesulf...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124418(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 261nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124424(4-[4-(tert-butyl)phenylsulfonamido]-2-cyclopropyl-...)copy SMILEScopy InChI
Affinity DataIC50: 299nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124430(4-tert-Butyl-N-[2-cyclopropyl-6-(2-ethanesulfonyla...)copy SMILEScopy InChI
Affinity DataIC50: 323nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124436(5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 351nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124428(5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 397nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124423(4-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyph...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124433(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 447nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124435(4-tert-Butyl-N-[6-(2-ethanesulfonylamino-ethoxy)-5...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124437(5-Methyl-pyridine-2-sulfonic acid [2-cyclopropyl-6...)copy SMILEScopy InChI
Affinity DataIC50: 582nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124451(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 587nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124433(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 724nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124435(4-tert-Butyl-N-[6-(2-ethanesulfonylamino-ethoxy)-5...)copy SMILEScopy InChI
Affinity DataIC50: 873nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124448(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 931nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124421(5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropy...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50124443(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50M9JPubMed
Displayed 1 to 50 (of 68 total ) | Next | Last >>* indicates data uncertainty>20%