Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126275(CHEMBL280793 | Isoquinolin-6-yl-(5-phenyl-oxazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126276(1-Isoquinolin-6-yl-3-m-tolyl-urea | CHEMBL27948)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126273((5-Phenyl-oxazol-2-yl)-quinazolin-7-yl-amine | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126265(1-Quinazolin-7-yl-3-m-tolyl-urea | CHEMBL26741)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126283(1-Isoquinolin-6-yl-3-p-tolyl-urea | CHEMBL29927)copy SMILEScopy InChI
Affinity DataIC50: 247nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126285(1-Benzyl-3-isoquinolin-6-yl-urea | CHEMBL29926)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126284(5-Bromo-isoquinolin-6-ylamine | CHEMBL27011)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126282(1-(5-Bromo-isoquinolin-6-yl)-3-phenyl-urea | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126268(1-Isoquinolin-6-yl-3-phenyl-urea | CHEMBL27529)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126270(5-Vinyl-isoquinolin-6-ylamine | CHEMBL26155)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126287(5-Chloro-isoquinolin-6-ylamine | CHEMBL416020)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126288(1-(5-Chloro-isoquinolin-6-yl)-3-phenyl-urea | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126280(1-Cinnolin-6-yl-3-m-tolyl-urea | CHEMBL26025)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126278(5-Allyl-isoquinolin-6-ylamine | CHEMBL282102)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126277(1-Isoquinolin-6-yl-3-o-tolyl-urea | CHEMBL27528)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126272(1-Isoquinolin-7-yl-3-phenyl-urea | CHEMBL283016)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126286(5-Bromo-6-methoxy-isoquinoline | CHEMBL26259)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126281(CHEMBL28687 | Isoquinolin-6-ylamine)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126279(CHEMBL285116 | N-Isoquinolin-6-yl-acetamide)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126267(CHEMBL29480 | N-(5-Bromo-isoquinolin-6-yl)-acetami...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126266(5-Propyl-isoquinolin-6-ylamine | CHEMBL285794)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126271(1-Phthalazin-6-yl-3-m-tolyl-urea | CHEMBL27189)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126264(5-Methyl-isoquinolin-6-ylamine | CHEMBL284662)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126274(CHEMBL27753 | Isoquinoline-5,6-diamine)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50126269(CHEMBL282997 | N-(5-Chloro-isoquinolin-6-yl)-aceta...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H3QPubMed
* indicates data uncertainty>20%