Compile Data Set for Download or QSAR

Found 41 hits of Enzyme Inhibition Constant Data   

TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135541(5-{(R)-2-Cyano-2-[(S)-2-(3-oxo-1,3-dihydro-isobenz...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135543(3-{(R)-2-Cyano-2-[(S)-2-(2-methyl-1,3-dioxo-2,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135533((S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135535(3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135537(3-{(R)-2-Cyano-2-[(S)-2-(3-oxo-indan-5-ylamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135546(3-{(R)-2-Cyano-2-[(S)-2-(3-oxo-1,3-dihydro-isobenz...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135532(3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135544(2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-t...)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135547(3-{(R)-2-Cyano-2-[(S)-2-(2-methyl-3-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135534(5-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135545(3-{(R)-2-Cyano-2-[(S)-2-(3-methanesulfonyl-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135548((S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135536(3-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135542((S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135532(3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135542((S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135540(4-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 282nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135535(3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135532(3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135535(3-{(R)-2-Cyano-2-[(S)-2-(1,1-dimethyl-3-oxo-1,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135539(3-[(R)-2-Cyano-2-((S)-3-phenyl-2-phenylamino-propi...)copy SMILEScopy InChI
Affinity DataIC50: 832nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135541(5-{(R)-2-Cyano-2-[(S)-2-(3-oxo-1,3-dihydro-isobenz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135547(3-{(R)-2-Cyano-2-[(S)-2-(2-methyl-3-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135543(3-{(R)-2-Cyano-2-[(S)-2-(2-methyl-1,3-dioxo-2,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135538((S)-N-[(R)-Cyano-(3-hydroxy-benzyloxymethyl)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135547(3-{(R)-2-Cyano-2-[(S)-2-(2-methyl-3-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135543(3-{(R)-2-Cyano-2-[(S)-2-(2-methyl-1,3-dioxo-2,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135533((S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135541(5-{(R)-2-Cyano-2-[(S)-2-(3-oxo-1,3-dihydro-isobenz...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135542((S)-N-((R)-Benzyloxymethyl-cyano-methyl)-2-phenyla...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135544(2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135534(5-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135534(5-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135544(2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135536(3-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135536(3-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135533((S)-N-[(R)-Cyano-(3-tetrazol-1-yl-benzyloxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135539(3-[(R)-2-Cyano-2-((S)-3-phenyl-2-phenylamino-propi...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135540(4-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135540(4-[(R)-2-Cyano-2-((S)-2-phenylamino-3-m-tolyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135539(3-[(R)-2-Cyano-2-((S)-3-phenyl-2-phenylamino-propi...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XZCPubMed
* indicates data uncertainty>20%