Compile Data Set for Download or QSAR

Found 31 hits of Enzyme Inhibition Constant Data   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141817(CHEMBL171509 | [1-(2-{4-[4-(4-tert-Butyl-phenylami...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141829((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141822((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141819((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141812(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-2-fluoro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141813(1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141823(2-[(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of c-Kit autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141810((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141832((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141821((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141824((4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(2-morpholin...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141814(CHEMBL276125 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141816(1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141811(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-3-fluoro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141831((4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(3-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141827(4-[4-(4-tert-Butyl-phenoxy)-phenoxy]-6,7-dimethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of PDGF-receptor autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141826(CHEMBL354830 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141830(4-[4-(4-tert-Butyl-benzyl)-phenoxy]-6,7-dimethoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141828((4-tert-Butyl-cyclohexyl)-[4-(6,7-dimethoxy-quinol...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141808(Biphenyl-4-yl-[4-(6,7-dimethoxy-quinolin-4-yloxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141825(CHEMBL172746 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGF-receptor autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141818(Biphenyl-3-yl-[4-(6,7-dimethoxy-quinolin-4-yloxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141815((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141820((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF-receptor 1 autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Kirin Brewery Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Met autophosphorylation of in intact cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16BVPubMed
* indicates data uncertainty>20%