Compile Data Set for Download or QSAR

Found 43 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119336(2-cyclohexyl-2-{3-phenyl-4-[4-(3-phenylpropyl)hexa...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141855(CHEMBL352981 | Cyclohexyl-{3-[4-(2-ethyl-4-pheneth...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141841(CHEMBL367837 | Cyclohexyl-{3-[4-(4-phenethyl-2-pro...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141839(CHEMBL435709 | {3-[4-(4-Benzyl-isoxazol-5-yl)-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141869(CHEMBL368183 | Cyclohexyl-{3-[4-(2-methyl-4-phenet...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141861(CHEMBL173064 | {3-[4-(4-Benzyl-isoxazol-3-yl)-pipe...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141856((R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration of the compound to displace [125I]-MIP-1 alpha from human CX3C chemokine receptor 5 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141858(CHEMBL367787 | Cyclohexyl-{3-[4-(4-phenethyl-2H-py...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141850(CHEMBL170543 | Cyclohexyl-(3-{4-[4-(difluoro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141856((R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration of the compound to displace [125I]-MIP-1 alpha from CX3C chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141848(CHEMBL367838 | Cyclohexyl-[3-[4-(2-ethyl-5-pheneth...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141845((R)-2-((3S,4S)-3-((4-(3-benzyl-1H-pyrazol-5-yl)pip...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141843((R)-2-cyclohexyl-2-((3S,4S)-3-((4-(1-ethyl-4-phene...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104249(CHEMBL81252 | {1-[(S)-4-(Benzenesulfonyl-methyl-am...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141838((R)-2-((3S,4S)-3-((4-(4-benzyl-1-ethyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141862((R)-2-((3S,4S)-3-((4-(3-benzyl-1-butyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141853(CHEMBL174303 | [3-{4-[5-(4-Chloro-phenyl)-2H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141863((R)-2-((3S,4S)-3-((4-(3-benzyl-1-methyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141844(CHEMBL172845 | Cyclohexyl-(3-phenyl-4-{4-[4-(1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141860((R)-2-((3S,4S)-3-((4-(3-benzyl-1-propyl-1H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141833((R)-2-((3S,4S)-3-((4-(4-benzyl-1H-pyrazol-5-yl)pip...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141865((3-{4-[5-Benzyl-2-(2,2,2-trifluoro-ethyl)-2H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141870(CHEMBL355749 | Cyclohexyl-(3-{4-[2-ethyl-4-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141851((3-{4-[5-(4-Cyano-phenyl)-2H-pyrazol-3-yl]-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141835(CHEMBL366439 | Cyclohexyl-{3-[4-(5-naphthalen-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141872(CHEMBL369189 | Cyclohexyl-{3-[4-(4-phenethyl-1-pro...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141847(CHEMBL170717 | Cyclohexyl-[3-{4-[5-(2,4-dichloro-p...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141871(CHEMBL368517 | {3-[4-(5-Benzyl-2-ethoxycarbonylmet...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141840(CHEMBL433980 | Cyclohexyl-(3-{4-[2-ethyl-4-(1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141837(CHEMBL173262 | Cyclohexyl-(3-{4-[4-(1-methyl-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141842(CHEMBL435526 | Cyclohexyl-(3-(3-fluoro-phenyl)-4-{...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141857(CHEMBL172944 | Cyclohexyl-[3-[4-(2-ethyl-5-naphtha...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141849((3-{4-[5-(4-Cyano-phenyl)-2-ethyl-2H-pyrazol-3-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141846((R)-2-((3S,4S)-3-((4-(4-benzyl-1-ethyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141836((R)-2-cyclohexyl-2-((3S,4S)-3-((4-(1-ethyl-3-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141859(CHEMBL413058 | {3-[4-(4-Benzoyl-2-ethyl-2H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141854(CHEMBL172721 | Cyclohexyl-{3-[4-(1-methyl-4-phenet...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human CX3C chemokine receptor 5 from GP120-membrane-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141864(CHEMBL174283 | {3-[4-(5-Benzyl-2-carboxymethyl-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141834(CHEMBL435724 | {3-[4-(4-Benzoyl-2H-pyrazol-3-yl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141866(CHEMBL367894 | {3-[4-(5-Benzyl-1-ethyl-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141852(CHEMBL173609 | {3-[4-(5-Benzyl-3-ethyl-pyrazol-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibitory activity of the compound against human Chemokine receptor 5 when co-administered with compound 8fMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141868(CHEMBL171911 | Cyclohexyl-{3-[4-(5-ethyl-3-pheneth...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibitory activity of the compound against human CX3C chemokine receptor 5 when co-administered with compound 8gMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141867((3-{4-[5-(4-Aminomethyl-phenyl)-2-ethyl-2H-pyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibitory activity against human CC chemokine receptor 5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FKPPubMed
* indicates data uncertainty>20%