Compile Data Set for Download or QSAR

Found 31 hits of Enzyme Inhibition Constant Data   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142026(3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142023(3-(5-Hydroxy-indan-1-ylidene)-1,3-dihydro-indol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366932(CHEMBL1794058)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366929(CHEMBL1794057)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142025(5-Bromo-3-(5-bromo-6-hydroxy-2'-methoxy-biphenyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366931(CHEMBL1794056)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142024(3-(1-Methyl-1H-indol-3-ylmethylene)-1,3-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142032(5-Bromo-3-(3-phenoxy-benzylidene)-1,3-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366930(CHEMBL1794059)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142025(5-Bromo-3-(5-bromo-6-hydroxy-2'-methoxy-biphenyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366929(CHEMBL1794057)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142024(3-(1-Methyl-1H-indol-3-ylmethylene)-1,3-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142026(3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142024(3-(1-Methyl-1H-indol-3-ylmethylene)-1,3-dihydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366931(CHEMBL1794056)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366932(CHEMBL1794058)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142023(3-(5-Hydroxy-indan-1-ylidene)-1,3-dihydro-indol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366929(CHEMBL1794057)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142023(3-(5-Hydroxy-indan-1-ylidene)-1,3-dihydro-indol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366931(CHEMBL1794056)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366930(CHEMBL1794059)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366930(CHEMBL1794059)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50366932(CHEMBL1794058)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142025(5-Bromo-3-(5-bromo-6-hydroxy-2'-methoxy-biphenyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142026(3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142032(5-Bromo-3-(3-phenoxy-benzylidene)-1,3-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of c-Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50142032(5-Bromo-3-(3-phenoxy-benzylidene)-1,3-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0TDFPubMed
* indicates data uncertainty>20%