Compile Data Set for Download or QSAR

Found 28 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6096(3-quinolinecarbonitrile 24 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6096(3-quinolinecarbonitrile 24 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6094(3-quinolinecarbonitrile 18 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6095(3-quinolinecarbonitrile 23 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMedDrugBank
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6099(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6094(3-quinolinecarbonitrile 18 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6095(3-quinolinecarbonitrile 23 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6105(4-phenylamino-3-quinolinecarbonitrile 23 | 6-Metho...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6103(4-phenylamino-3-quinolinecarbonitrile 21 | 6-Metho...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6099(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6102(4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[(...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6101(3-quinolinecarbonitrile 20 | 4-phenylamino-3-quino...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6105(4-phenylamino-3-quinolinecarbonitrile 23 | 6-Metho...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6100(3-quinolinecarbonitrile 19 | 4-[(2,4-Dichloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6100(3-quinolinecarbonitrile 19 | 4-[(2,4-Dichloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6103(4-phenylamino-3-quinolinecarbonitrile 21 | 6-Metho...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6101(3-quinolinecarbonitrile 20 | 4-phenylamino-3-quino...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6098(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6104(4-[(2,4-Dimethylphenyl)amino]-6-methoxy-7-[(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6098(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6097(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6106(4-[(2,4-Dichloro-5-ethoxyphenyl)amino]-6-methoxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM6106(4-[(2,4-Dichloro-5-ethoxyphenyl)amino]-6-methoxy-7...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
* indicates data uncertainty>20%