Compile Data Set for Download or QSAR

Found 26 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 155nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 189nMAssay Description:Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 521nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JQPPubMed
* indicates data uncertainty>20%