Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148286(2-{(S)-3-[4-(2-Benzyl-thiazol-5-yl)-piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148285(2-{(S)-3-[4-(2-Benzyl-thiazol-5-yl)-piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249465((R)-2-((3S,4S)-3-((4-(2-benzylthiazol-5-yl)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249467((R)-2-((3S,4S)-3-((4-(2-benzyloxazol-5-yl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404275(CHEMBL2112559)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249334((R)-2-((3S,4S)-3-((4-(2-benzylthiazol-5-yl)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404276(CHEMBL2112558)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404274(CHEMBL2112557)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249302((R)-2-((3S,4S)-3-((4-(2-benzyl-1H-imidazol-5-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404272(CHEMBL2112552)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404278(CHEMBL2112560)copy SMILEScopy InChI
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404277(CHEMBL2112553)copy SMILEScopy InChI
Affinity DataIC50: 0.760nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404273(CHEMBL2112556)copy SMILEScopy InChI
Affinity DataIC50: 0.890nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404280(CHEMBL2112555)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50404279(CHEMBL2112554)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249303((R)-2-((3S,4S)-3-((4-(2-benzylthiazol-4-yl)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249304((R)-2-((3S,4S)-3-((4-(5-benzyloxazol-2-yl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249466((R)-2-((3S,4S)-3-((4-(2-benzyloxazol-5-yl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249430((R)-2-((3S,4S)-3-((4-(5-benzylthiazol-2-yl)piperid...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249333((R)-2-((3S,4S)-3-((4-(2-benzyloxazol-5-yl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249429((R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(2-phen...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249332((R)-2-((3S,4S)-3-((4-(2-benzyl-1H-imidazol-5-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249395((R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(3-phen...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibitory concentration of the compound against C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249428((R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249396((R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human C-C chemokine receptor type 5 assayed using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63MD1PubMed
* indicates data uncertainty>20%