Compile Data Set for Download or QSAR

Found 41 hits of Enzyme Inhibition Constant Data   

TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148310(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148292(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 0.350nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148298(((S)-1-Formyl-pentyl)-carbamic acid (R)-1-benzyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148307(((S)-1-Formyl-pentyl)-carbamic acid 1-isopropyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148300(((S)-1-Formyl-pentyl)-carbamic acid 1-propyl-butyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.870nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148314(((S)-1-Formyl-pentyl)-carbamic acid 1-isobutyl-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148297(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148296(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148294(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148299(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-1-eth...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148293(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148291(((S)-1-Formyl-pentyl)-carbamic acid (S)-2-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148312(((S)-1-Formyl-pentyl)-carbamic acid 2-(4-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148295(((S)-1-Formyl-pentyl)-carbamic acid 2-(2-chloro-ph...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148305(((S)-1-Formyl-pentyl)-carbamic acid 1-ethyl-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148303(((S)-1-Formyl-pentyl)-carbamic acid 2-(4-chloro-ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148316(((S)-1-Formyl-pentyl)-carbamic acid 1-isopropyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148308(((S)-1-Formyl-pentyl)-carbamic acid 2-(3-methoxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148313(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148315(((S)-1-Formyl-pentyl)-carbamic acid 1,1-dimethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148311(((S)-1-Formyl-pentyl)-carbamic acid 1,1-dimethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetProcathepsin L(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148310(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin L was determined in a fluorescence assay using 5 microM Cbz-Phe-Arg-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50137790(((S)-1-Formyl-pentyl)-carbamic acid tert-butyl est...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148301(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-2-phe...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148310(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin B was determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148304(((S)-1-Formyl-pentyl)-carbamic acid (R)-1-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetProcathepsin L(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148299(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-1-eth...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin L was determined in a fluorescence assay using 5 microM Cbz-Phe-Arg-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetProcathepsin L(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148291(((S)-1-Formyl-pentyl)-carbamic acid (S)-2-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin L was determined in a fluorescence assay using 5 microM Cbz-Phe-Arg-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148309(((S)-1-Formyl-pentyl)-carbamic acid phenethyl este...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148291(((S)-1-Formyl-pentyl)-carbamic acid (S)-2-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin B was determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148296(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin B was determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148306(((S)-1-Formyl-pentyl)-carbamic acid benzyl ester |...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin K(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148302(((S)-1-Formyl-pentyl)-carbamic acid 3-phenyl-propy...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against recombinant human cathepsin K determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetProcathepsin L(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148296(((S)-1-Formyl-pentyl)-carbamic acid (S)-1-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin L was determined in a fluorescence assay using 5 microM Cbz-Phe-Arg-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148292(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin B was determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetProcathepsin L(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148293(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin L was determined in a fluorescence assay using 5 microM Cbz-Phe-Arg-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetProcathepsin L(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148292(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin L was determined in a fluorescence assay using 5 microM Cbz-Phe-Arg-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148299(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-1-eth...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin B was determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148293(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin B was determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetProcathepsin L(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148294(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin L was determined in a fluorescence assay using 5 microM Cbz-Phe-Arg-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
TargetCathepsin B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50148294(((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration of the compound against recombinant human cathepsin B was determined in a fluorescence assay using 10 microM Cbz-Phe-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2VMDPubMed
* indicates data uncertainty>20%