Compile Data Set for Download or QSAR

Found 34 hits of Enzyme Inhibition Constant Data   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152049(3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-et...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152033(7-(1-Cyclopropyl-butyl)-3-(2,4-dichloro-phenyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152054(7-(1-Cyclopropyl-propyl)-3-(2,4-dichloro-phenyl)-8...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152059(3-(2,4-Dichloro-phenyl)-8-ethyl-7-(1-ethyl-pentyl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152043(8-Ethyl-1-methyl-7-(1-propyl-butyl)-3-(2,4,6-trime...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152031(7-(1-Cyclobutyl-ethyl)-3-(2,4-dichloro-phenyl)-8-e...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152055(3-(2-Chloro-4-methoxy-phenyl)-8-ethyl-1-methyl-7-(...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152044(3-(2,4-Dichloro-phenyl)-8-ethyl-7-(1-methoxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152030(3-(2-Chloro-4-isopropyl-phenyl)-8-ethyl-1-methyl-7...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152035(3-(2,4-Dichloro-phenyl)-8-ethyl-7-(1-ethyl-2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152037(3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152038(3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-prop...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152056(7-(1-Cyclopropyl-ethyl)-3-(2,4-dichloro-phenyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152053(3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-prop...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152034(3-(2,4-Dichloro-phenyl)-8-ethyl-7-(1-ethyl-propyl)...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152040(3-(2-Chloro-4-methoxy-phenyl)-7-(1-cyclopropyl-pro...)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152051(8-Ethyl-3-(4-methoxy-2-pyridin-3-ylmethyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 161nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152061(3-(4-Chloro-phenyl)-8-ethyl-1-methyl-7-(1-propyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152048(8-Ethyl-1-methyl-7-(1-propyl-butyl)-3-(2,4,6-trime...)copy SMILEScopy InChI
Affinity DataIC50: 191nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152042(7-Biphenyl-4-ylmethyl-3-(2,4-dichloro-phenyl)-8-et...)copy SMILEScopy InChI
Affinity DataIC50: 324nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152039(3-(2,4-Dichloro-phenyl)-8-ethyl-1,2-dimethyl-7-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 383nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152045(3-(2,4-Dichloro-phenyl)-8-ethyl-7-(4-methoxy-benzy...)copy SMILEScopy InChI
Affinity DataIC50: 456nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152036(3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 458nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152057(3-(2-Chloro-4-isopropyl-phenyl)-8-ethyl-7-(1-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 555nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152032(3-(2,4-Dichloro-phenyl)-2,8-diethyl-1-methyl-7-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 626nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152060(7-Benzyloxymethyl-3-(2,4-dichloro-phenyl)-8-ethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152058(3-(2-Chloro-4-methoxy-phenyl)-8-ethyl-1-methyl-7-(...)copy SMILEScopy InChI
Affinity DataIC50: 875nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152041(3-(2,4-Dichloro-phenyl)-1-methyl-7-(1-propyl-butyl...)copy SMILEScopy InChI
Affinity DataIC50: 898nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152052(8-Ethyl-3-(4-methoxy-2-methyl-5-pyridin-3-yl-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152047(3-(2,4-Dichloro-phenyl)-8-ethyl-7-(1-ethyl-propyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152046(3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-naphtha...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152050(5-(2,4-Dichloro-phenylamino)-2-ethyl-3-(1-ethyl-pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152049(3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-et...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]- sauvagine binding to corticotropin releasing factor receptor 2 of porcine choroid plexusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152038(3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-prop...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]- sauvagine binding to corticotropin releasing factor receptor 2 of porcine choroid plexusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WBBPubMed
* indicates data uncertainty>20%