Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMedDrugBank
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6071(7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-{4-[(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6442(7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-{3-[(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6441(7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-[4-(morp...)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6084(7-[(2,4-dichlorophenyl)amino]-2-{4-[(4-methylpiper...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6439(7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-phenylth...)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6447(7-(2,4-dichlorophenoxy)-2-{4-[(4-methylpiperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 580nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6445(4-[(2,4-dichloro-5-methoxyphenyl)amino]-2-[4-(morp...)copy SMILEScopy InChI
Affinity DataIC50: 830nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6438(7-[(2,4-dichloro-5-methoxyphenyl)amino]thieno[3,2-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6443(7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-{2-[(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6444(7-[(2,4-dichloro-5-methoxyphenyl)amino]-3-[4-(morp...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4FXNPubMed
* indicates data uncertainty>20%