Compile Data Set for Download or QSAR

Found 39 hits of Enzyme Inhibition Constant Data   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164782((4R,4aR,5R)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164784((4S,7S)-4-Methyl-octahydro-[1]pyrindin-(2E)-yliden...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164779((4R,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164782((4R,4aR,5R)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164784((4S,7S)-4-Methyl-octahydro-[1]pyrindin-(2E)-yliden...)copy SMILEScopy InChI
Affinity DataIC50: 133nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164781((5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 186nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164779((4R,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164780(4-Methyl-3,4-dihydro-1H-quinolin-(2E)-ylideneamine...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164781((5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164783((5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 528nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164783((5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164778((4S,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164782((4R,4aR,5R)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164776((4R,6R,9R)-4-Methyl-decahydro-cyclohepta[b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164784((4S,7S)-4-Methyl-octahydro-[1]pyrindin-(2E)-yliden...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164780(4-Methyl-3,4-dihydro-1H-quinolin-(2E)-ylideneamine...)copy SMILEScopy InChI
Affinity DataIC50: 974nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164776((4R,6R,9R)-4-Methyl-decahydro-cyclohepta[b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164779((4R,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164776((4R,6R,9R)-4-Methyl-decahydro-cyclohepta[b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062129(3,4-Dihydro-1H-quinolin-(2E)-ylideneamine | 3,4-Di...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164778((4S,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164778((4S,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164783((5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164781((5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062129(3,4-Dihydro-1H-quinolin-(2E)-ylideneamine | 3,4-Di...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164780(4-Methyl-3,4-dihydro-1H-quinolin-(2E)-ylideneamine...)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062129(3,4-Dihydro-1H-quinolin-(2E)-ylideneamine | 3,4-Di...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8F3MPubMed
* indicates data uncertainty>20%