Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9893(2-(1H-Imidazol-1-yl)-3-phenyl-7-(benzyloxy)-4H-1-b...)copy SMILEScopy InChI
Affinity DataKi:  250nM ΔG°:  -39.2kJ/mole IC50: 520nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9891(2-(1H-Imidazol-1-yl)-7-methoxy-3-phenyl-4H-1-benzo...)copy SMILEScopy InChI
Affinity DataKi:  680nM ΔG°:  -36.6kJ/mole IC50: 770nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9892(2-(1H-Imidazol-1-yl)-7-methoxy-3-(4-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+3nM ΔG°:  -34.1kJ/mole IC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9894(2-(1H-Imidazol-1-yl)-3-(4-methoxyphenyl)-7-(benzyl...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+3nM ΔG°:  -31.8kJ/mole IC50: 4.70E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nM ΔG°:  -29.2kJ/mole IC50: 3.40E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9895(7-Methoxy-3-phenyl-2-(1H-1,2,4-triazol-1-yl)-4H-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9897(2-thioazole isoflavone analog 3c | 7-Methoxy-2-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9898(2-thioazole isoflavone analog 3d | 7-Methoxy-3-phe...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
TargetAromatase(Homo sapiens (Human))
Ohio State University

LigandPNGBDBM9896(2-(1H-Imidazolyl-2-thio)-7-methoxy-3-phenyl-4H-1-b...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMed
* indicates data uncertainty>20%