Compile Data Set for Download or QSAR

Found 188 hits of Enzyme Inhibition Constant Data   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6151(1,6-naphthyridine 20 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6157(1,6-naphthyridine 26 | 3-tert-butyl-1-(7-{[5-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6178(1,6-naphthyridine 75 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6148(1,6-naphthyridine 17 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6154(1,6-naphthyridine 23 | 3-tert-butyl-1-(7-{[4-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6180(1,6-naphthyridine 77 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6150(1,6-naphthyridine 19 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6155(1,6-naphthyridine 24 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6156(1,6-naphthyridine 25 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6179(1,6-naphthyridine 76 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4618(1,6-naphthyridine 14 | 1,6-naphthyridine deriv. 20...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.8 T: 2°CAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6168(1,6-naphthyridine 37 | 3-tert-butyl-1-[3-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6165(1,6-naphthyridine 34 | 3-tert-butyl-1-[3-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6167(1,6-naphthyridine 36 | 1-[3-(2,6-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6149(1,6-naphthyridine 18 | 3-tert-butyl-1-(7-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.8 T: 2°CAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6164(1,6-naphthyridine 33 | 1-[3-(2,6-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6165(1,6-naphthyridine 34 | 3-tert-butyl-1-[3-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6188(3-tert-butyl-1-[6-(3,5-dimethoxyphenyl)-2-{[3-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6147(1,6-naphthyridine 16 | 1-[3-(3,5-dimethoxyphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6188(3-tert-butyl-1-[6-(3,5-dimethoxyphenyl)-2-{[3-(4-m...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6151(1,6-naphthyridine 20 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6153(1,6-naphthyridine 22 | 1-(7-{[4-(diethylamino)buty...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6148(1,6-naphthyridine 17 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6154(1,6-naphthyridine 23 | 3-tert-butyl-1-(7-{[4-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6168(1,6-naphthyridine 37 | 3-tert-butyl-1-[3-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6168(1,6-naphthyridine 37 | 3-tert-butyl-1-[3-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6165(1,6-naphthyridine 34 | 3-tert-butyl-1-[3-(2,6-dich...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6190(3-tert-butyl-1-(2-{[4-(diethylamino)butyl]amino}-6...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6157(1,6-naphthyridine 26 | 3-tert-butyl-1-(7-{[5-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6167(1,6-naphthyridine 36 | 1-[3-(2,6-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6150(1,6-naphthyridine 19 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4618(1,6-naphthyridine 14 | 1,6-naphthyridine deriv. 20...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6164(1,6-naphthyridine 33 | 1-[3-(2,6-dichlorophenyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6155(1,6-naphthyridine 24 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6187(1-[6-(3,5-dimethoxyphenyl)-2-{[3-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6189(1-(2-{[4-(diethylamino)butyl]amino}-6-(3,5-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6191(3-tert-butyl-1-[6-(3,5-dimethoxyphenyl)-2-[(3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6166(1,6-naphthyridine 35 | 3-(2,6-Dichlorophenyl)-N7-[...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6146(1,6-naphthyridine 15 | 3-(3,5-Dimethoxyphenyl)-N7-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6153(1,6-naphthyridine 22 | 1-(7-{[4-(diethylamino)buty...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6178(1,6-naphthyridine 75 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6147(1,6-naphthyridine 16 | 1-[3-(3,5-dimethoxyphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMpH: 7.8 T: 2°CAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6179(1,6-naphthyridine 76 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6159(1,6-naphthyridine 28 | 3-tert-butyl-1-(7-{[3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6149(1,6-naphthyridine 18 | 3-tert-butyl-1-(7-{[3-(diet...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6187(1-[6-(3,5-dimethoxyphenyl)-2-{[3-(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6163(1,6-naphthyridine 32 | 3-(2,6-dichlorophenyl)-7-N-...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6156(1,6-naphthyridine 25 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6191(3-tert-butyl-1-[6-(3,5-dimethoxyphenyl)-2-[(3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6169(1,6-naphthyridine 38 | N-[3-(Benzyloxy)propyl]-N-[...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
Displayed 1 to 50 (of 188 total ) | Next | Last >>* indicates data uncertainty>20%