Compile Data Set for Download or QSAR

Found 32 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173389(CHEMBL198150 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173388(CHEMBL197641 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173383(CHEMBL199118 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173398(CHEMBL371691 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173393(4-[3-(4-{Ethyl-[2-(4-methanesulfonyl-phenyl)-acety...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173391(CHEMBL370826 | N-{1-[3-(4-Acetylamino-phenyl)-3-(3...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173378(CHEMBL198277 | N-{1-[3-(4-Chloro-phenyl)-3-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173382(CHEMBL373214 | N-Ethyl-N-{1-[3-(3-fluoro-phenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173380(CHEMBL372733 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173395(CHEMBL372134 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50157000(CHEMBL180155 | N-Allyl-N-[1-(3,3-diphenyl-propyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173376(CHEMBL198114 | N-Ethyl-N-{1-[3-(4-methanesulfonyla...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50157032(CHEMBL369311 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173386(CHEMBL370998 | N-{1-[3-(4-Chloro-phenyl)-3-(3-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173397(CHEMBL370552 | N-{4-[3-(4-{Ethyl-[2-(4-methanesulf...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173376(CHEMBL198114 | N-Ethyl-N-{1-[3-(4-methanesulfonyla...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of MIP-1beta stimulated calcium transients in CCR5-expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173374(CHEMBL198497 | N-{1-[3-(4-Acetylamino-phenyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173381(CHEMBL197714 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50157026(CHEMBL182074 | N-Cyclopropyl-N-[1-(3,3-diphenyl-pr...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173384(CHEMBL197907 | N-{1-[3-(3-Chloro-phenyl)-3-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173392(CHEMBL371865 | N-{1-[3-(3,4-Dichloro-phenyl)-3-phe...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173377(CHEMBL372297 | N-[1-(3-Biphenyl-4-yl-3-phenyl-prop...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50410486(CHEMBL2113131)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173387(CHEMBL372640 | N-{1-[3-(4-Amino-phenyl)-3-(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173385(CHEMBL199119 | N-{4-[3-(4-{Ethyl-[2-(4-methanesulf...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173396(CHEMBL382079 | N-{1-[3-(4-tert-Butoxyamino-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173373(CHEMBL369947 | N-{1-[3-(4-Amino-phenyl)-3-phenyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173390(4-[3-(4-{Ethyl-[2-(4-methanesulfonyl-phenyl)-acety...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173394(CHEMBL199258 | N-Ethyl-N-{1-[3-(4-fluoro-phenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173371(CHEMBL198884 | N-{1-[3-(4-Benzenesulfonylamino-phe...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173379(CHEMBL372852 | N-{1-[3,3-Bis-(4-chloro-phenyl)-pro...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50173399(CHEMBL199147 | N-(1-(3,3-bis(4-fluorophenyl)propyl...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SFGPubMed
* indicates data uncertainty>20%