Compile Data Set for Download or QSAR

Found 46 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174939(CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174932(CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174934(CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174935(CHEMBL371688 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174929(CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM12229(AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174937(CHEMBL198946 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174930(1-(4-(3-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174938(CHEMBL425209 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174932(CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174928(CHEMBL200231 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174929(CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174940(CHEMBL197339 | N-(5-chloro-2-methoxypyridin-4-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174931(CHEMBL198752 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174935(CHEMBL371688 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174939(CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174934(CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174941(CHEMBL197186 | N-(5-chloro-2-methoxypyridin-4-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174938(CHEMBL425209 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174937(CHEMBL198946 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174929(CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM12232(AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174932(CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM12229(AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174940(CHEMBL197339 | N-(5-chloro-2-methoxypyridin-4-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Src-transfected 3T3 cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174941(CHEMBL197186 | N-(5-chloro-2-methoxypyridin-4-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against c-Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM12229(AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174935(CHEMBL371688 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174931(CHEMBL198752 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174934(CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174928(CHEMBL200231 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174930(1-(4-(3-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174936(1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174938(CHEMBL425209 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174937(CHEMBL198946 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174939(CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174933(1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Centre de Recherches

Curated by ChEMBL
LigandPNGBDBM50174942(1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DWCPubMed
* indicates data uncertainty>20%