Compile Data Set for Download or QSAR

Found 46 hits of Enzyme Inhibition Constant Data   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  8.5nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  9.10nMAssay Description:Binding affinity to human 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Binding affinity to adrenergic alpha-2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Binding affinity to adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Binding affinity to adrenergic beta-2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Binding affinity to human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  229nMAssay Description:Binding affinity to human 5HT5A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  302nMAssay Description:Binding affinity to histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Binding affinity to adrenergic alpha-2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  407nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  476nMAssay Description:Binding affinity to adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  480nMAssay Description:Binding affinity to sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  1.01E+3nMAssay Description:Binding affinity to adrenergic alpha-2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  6.14E+3nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  6.98E+3nMAssay Description:Binding affinity to NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+3nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to hERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to vasopressin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetTumor necrosis factor receptor superfamily member 16(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to neurotrophin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to MDR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to VMAT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adrenergic beta-3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to adenosine A4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to Delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetVasopressin V1a/V1b receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to vasopressin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
TargetChromaffin granule amine transporter(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to VMAT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataEC50:  0.0500nMAssay Description:Agonistic activity at human 5HT1A receptor by [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50180054(CHEMBL199824 | [O-methyl-11C]2-{4-[4-(7-methoxynap...)copy SMILEScopy InChI
Affinity DataEC50:  0.0100nMAssay Description:Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49QBDPubMed
* indicates data uncertainty>20%