Compile Data Set for Download or QSAR

Found 29 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184396((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184399((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-[(1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184398((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184400((S)-(-)-9-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184402((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184403(7-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-N-(4-((1-p...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184398((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184399((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-[(1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184398((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184403(7-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-N-(4-((1-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184400((S)-(-)-9-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184402((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184399((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-[(1-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184396((S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184401((S)-(-)-9-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184403(7-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-N-(4-((1-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of replication of R5 HIV1 Ba-L in MOLT4/CCR5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]MCP-1 from CCR2b expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184400((S)-(-)-9-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184404((S)-(-)-10-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50184405((S)-(-)-10-{4-[2-( butoxy)ethoxy]phenyl}-1-isobuty...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Displacement of [125I]RANTES from CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [125I]TARC from CCR4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of [125I]eotaxin from CCR3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 7(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]MIP-3beta from CCR7 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50422828(CENICRIVIROC | CENICRIVIROC MESYLATE | TAK-652 | T...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]RANTES from CCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2303PubMed
* indicates data uncertainty>20%