Compile Data Set for Download or QSAR

Found 27 hits of Enzyme Inhibition Constant Data   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185601(CHEMBL380059)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMedDrugBank
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185595((E)-2-(N-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185585((E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185590((2-{[(2E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185596((E)-5-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185604((E)-2-((4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185603((E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 168nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185599((E)-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185587(7-hydroxy-5-methoxy-4-methyl-6-(3-methylbut-2-enyl...)copy SMILEScopy InChI
Affinity DataIC50: 254nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185594((E)-7-hydroxy-5-methoxy-6-(4-methoxy-3-methylbut-2...)copy SMILEScopy InChI
Affinity DataIC50: 273nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185588((E)-dimethyl 4-(4-hydroxy-6-methoxy-7-methyl-3-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 289nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185598((2-{[(E)-4-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3...)copy SMILEScopy InChI
Affinity DataIC50: 498nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185602((E)-2-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 499nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185600((1E,3E)-5-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 506nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185597((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)copy SMILEScopy InChI
Affinity DataIC50: 749nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185583((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)copy SMILEScopy InChI
Affinity DataIC50: 785nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185593((E)-diethyl 2-(4-(4-hydroxy-6-methoxy-7-methyl-3-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185591((E)-2-((4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Gilead Sciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50185584((E)-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6JP9PubMed
* indicates data uncertainty>20%