Compile Data Set for Download or QSAR

Found 41 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185979(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.420nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185967(CHEMBL207487 | N-(3-(4-(4-(methylsulfonyl)benzyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185972(CHEMBL207182 | N-(3-(4-(4-fluorobenzyl)piperidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185973(CHEMBL207630 | N-{3-[4-(4-cyanobenzyl)piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185973(CHEMBL207630 | N-{3-[4-(4-cyanobenzyl)piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185963(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185963(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185964(CHEMBL382252 | N-{3-[4-(3-carbamoylbenzyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185961(CHEMBL207190 | N-(3-(4-(4-fluorobenzyl)piperidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185978(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185967(CHEMBL207487 | N-(3-(4-(4-(methylsulfonyl)benzyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185975(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185964(CHEMBL382252 | N-{3-[4-(3-carbamoylbenzyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185968(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185972(CHEMBL207182 | N-(3-(4-(4-fluorobenzyl)piperidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185975(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185961(CHEMBL207190 | N-(3-(4-(4-fluorobenzyl)piperidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185979(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185978(1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185968(1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185971(CHEMBL207447 | N-(3,4-dichlorophenyl)-N-[3-(4-{[(4...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185970(CHEMBL207301 | methyl 4-({1-[3-((3,4-Dichloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185971(CHEMBL207447 | N-(3,4-dichlorophenyl)-N-[3-(4-{[(4...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185969(CHEMBL264832 | N-(3,4-dichlorophenyl)-N-(3-{4-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185980(CHEMBL207485 | N-{3-[4-(4-carbamoylbenzyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185966(CHEMBL206088 | N-{3-[4-(2-carbamoylbenzyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185970(CHEMBL207301 | methyl 4-({1-[3-((3,4-Dichloropheny...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185976(CHEMBL205706 | N-(3,4-dichlorophenyl)-N-(3-{4-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185980(CHEMBL207485 | N-{3-[4-(4-carbamoylbenzyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185969(CHEMBL264832 | N-(3,4-dichlorophenyl)-N-(3-{4-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185974(CHEMBL205964 | N-(3-{4-[4-(tert-butylcarbamoyl)ben...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185974(CHEMBL205964 | N-(3-{4-[4-(tert-butylcarbamoyl)ben...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185966(CHEMBL206088 | N-{3-[4-(2-carbamoylbenzyl)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185960(1-acetyl-N-(3-(4-benzylpiperidin-1-yl)propyl)-N-ph...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185976(CHEMBL205706 | N-(3,4-dichlorophenyl)-N-(3-{4-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185965(1-acetyl-N-(3,4-dichlorophenyl)-N-{3-[4-(4-fluoroa...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185965(1-acetyl-N-(3,4-dichlorophenyl)-N-{3-[4-(4-fluoroa...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185977(4-({1-[3-((3,4-dichlorophenyl){[1-(methylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185977(4-({1-[3-((3,4-dichlorophenyl){[1-(methylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185960(1-acetyl-N-(3-(4-benzylpiperidin-1-yl)propyl)-N-ph...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50185962(CHEMBL210327 | N-(3,4-dichlorophenyl)-N-(3-{4-[(4-...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5G8FPubMed
* indicates data uncertainty>20%