Compile Data Set for Download or QSAR

Found 38 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188387((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-amino-2...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188390(4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentame...)copy SMILEScopy InChI
Affinity DataIC50: 144nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188387((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-amino-2...)copy SMILEScopy InChI
Affinity DataIC50: 172nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188386(2-((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-(met...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188390(4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentame...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188386(2-((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-(met...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMedMMDB
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188387((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-amino-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(CHEMBL210465 | N-(3,4-dimethoxyphenethyl)-4,7,7-tr...)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188390(4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentame...)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of GR-mediated transactivation of galactosidase reporter gene in HEK293 cells expressing 11betaHSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188388((R)-2-((2S,4aR,6S,6aS,6bR,8aR,10S,12aS,12bR,14bR)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188388((R)-2-((2S,4aR,6S,6aS,6bR,8aR,10S,12aS,12bR,14bR)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMedMMDB
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of human recombinant 17-beta-HSD2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188386(2-((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-(met...)copy SMILEScopy InChI
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(CHEMBL210465 | N-(3,4-dimethoxyphenethyl)-4,7,7-tr...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of 11-beta-HSD1-dependent cortisone conversion to cortisol in mouse intact 3T3 L1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188390(4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentame...)copy SMILEScopy InChI
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(CHEMBL210465 | N-(3,4-dimethoxyphenethyl)-4,7,7-tr...)copy SMILEScopy InChI
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of 11-beta-HSD1-dependent cortisone conversion to cortisol in mouse intact C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(CHEMBL210465 | N-(3,4-dimethoxyphenethyl)-4,7,7-tr...)copy SMILEScopy InChI
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188387((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-amino-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.04E+3nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188391(4-(2,4-dichlorophenyl)-2-hydroxy-3-(4-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 7.44E+3nMAssay Description:Inhibition of human recombinant 17-beta-HSD2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188391(4-(2,4-dichlorophenyl)-2-hydroxy-3-(4-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of human recombinant 11betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188386(2-((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-(met...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human recombinant 17-beta-HSD2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188390(4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentame...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of GR-mediated transactivation of galactosidase reporter gene in HEK293 cells in absence of 11betaHSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188388((R)-2-((2S,4aR,6S,6aS,6bR,8aR,10S,12aS,12bR,14bR)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human recombinant 17betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188389(CHEMBL210465 | N-(3,4-dimethoxyphenethyl)-4,7,7-tr...)copy SMILEScopy InChI
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human recombinant 17betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188390(4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentame...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity against MRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188388((R)-2-((2S,4aR,6S,6aS,6bR,8aR,10S,12aS,12bR,14bR)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human recombinant 17-beta-HSD2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188390(4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentame...)copy SMILEScopy InChI
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of human recombinant 17-beta-HSD2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188388((R)-2-((2S,4aR,6S,6aS,6bR,8aR,10S,12aS,12bR,14bR)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant 17betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188391(4-(2,4-dichlorophenyl)-2-hydroxy-3-(4-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188391(4-(2,4-dichlorophenyl)-2-hydroxy-3-(4-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant 17betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188387((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-amino-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant 17betaHSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188386(2-((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-(met...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50188391(4-(2,4-dichlorophenyl)-2-hydroxy-3-(4-methoxy-3-me...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant 11-beta-HSD1 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN958FPubMed
* indicates data uncertainty>20%