Compile Data Set for Download or QSAR

Found 86 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190525((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-methoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190521(9-(4-allyloxyphenylmethyl)-1-butyl-3-cyclohexyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190524(3-(2-methylpropyl)-9-(4-phenoxyphenylmethyl)-1-pro...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190523(1-butyl-9-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190521(9-(4-allyloxyphenylmethyl)-1-butyl-3-cyclohexyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190525((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-methoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190523(1-butyl-9-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Binding affinity to sigma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190515((3R)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190524(3-(2-methylpropyl)-9-(4-phenoxyphenylmethyl)-1-pro...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190515((3R)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of radio-isotope labeled MIP1-alpha binding to human recombinant CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190514((3S)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 2.07E+3nMAssay Description:Binding affinity to muscarinic M3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190512((3R)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190526((3S)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazas...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190517((3R)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazas...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Antagonist activity against human recombinant CCR5 expressed in CHO cells assessed as inhibition of human MIP-1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of radio-isotope labeled SDF1-alpha binding to human recombinant CXCR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190514((3S)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190514((3S)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR4 expressed in CHO cells assessed as inhibition of human MCD-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR2 expressed in CHO cells assessed as inhibition of human MCP1-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of radio-isotope labeled SDF1-alpha binding to human recombinant CXCR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of radio-isotope labeled SDF1-alpha binding to human recombinant CXCR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR4 expressed in CHO cells assessed as inhibition of human MCD-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR2 expressed in CHO cells assessed as inhibition of human MCP1-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190512((3R)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR2 expressed in CHO cells assessed as inhibition of human MCP1-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190523(1-butyl-9-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR2 expressed in CHO cells assessed as inhibition of human MCP1-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190523(1-butyl-9-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of radio-isotope labeled MCP1 binding to human recombinant CCR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190518(1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of radio-isotope labeled SDF1-alpha binding to human recombinant CXCR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190521(9-(4-allyloxyphenylmethyl)-1-butyl-3-cyclohexyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of radio-isotope labeled SDF1-alpha binding to human recombinant CXCR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190522((RS)-9-benzyl-1-butyl-3-isobutyl-1,4,9-triazaspiro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of radio-isotope labeled SDF1-alpha binding to human recombinant CXCR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190520((RS)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR2 expressed in CHO cells assessed as inhibition of human MCP1-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190513((RS)-1-butyl-3-(cyclohexylmethyl)-9-((2,3-dihydrob...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190519((3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR4 expressed in CHO cells assessed as inhibition of human MCD-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190515((3R)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CXCR4 expressed in CHO cells assessed as inhibition of human SDF1-alpha-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50190521(9-(4-allyloxyphenylmethyl)-1-butyl-3-cyclohexyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant CCR2 expressed in CHO cells assessed as inhibition of human MCP1-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T1SPubMed
Displayed 1 to 50 (of 86 total ) | Next | Last >>* indicates data uncertainty>20%