Compile Data Set for Download or QSAR

Found 14 hits of Enzyme Inhibition Constant Data   

TargetEndothelin-1 receptor(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197001(CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197003(CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197002(CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197000(CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197004(3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50196999(CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)copy SMILEScopy InChI
Affinity DataIC50: 21.6nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197005(CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...)copy SMILEScopy InChI
Affinity DataIC50: 44.9nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197003(CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197002(CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197000(CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...)copy SMILEScopy InChI
Affinity DataIC50: 4.51E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197004(3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.69E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50196999(CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)copy SMILEScopy InChI
Affinity DataIC50: 4.92E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197001(CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
CovX Research LLC

Curated by ChEMBL
LigandPNGBDBM50197005(CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ07ZFPubMed
* indicates data uncertainty>20%