Compile Data Set for Download or QSAR

Found 40 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197982(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197996(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197988(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197982(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197984((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197978(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197988(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197993((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197995((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197981(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197984((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197999(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197996(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197991(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197980(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197993((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 118nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197978(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197989(4-(3-(3-chlorophenyl)-1-(naphthalen-2-yl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 168nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197999(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 178nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197995((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198000(CHEMBL391668 | N-(5-(diethylamino)pentan-2-yl)-4-(...)copy SMILEScopy InChI
Affinity DataIC50: 207nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197980(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 209nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197980(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197995((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 221nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197991(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 225nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197981(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197983(4-(3-(4-chlorophenyl)-1-(naphthalen-2-yl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 442nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197985(CHEMBL239569 | N-(5-(diethylamino)pentan-2-yl)-4-(...)copy SMILEScopy InChI
Affinity DataIC50: 522nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197992(4-(3-(3,5-bis(trifluoromethyl)phenyl)-1-(naphthale...)copy SMILEScopy InChI
Affinity DataIC50: 634nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197977(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197979(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197977(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197982(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198001(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197998(CHEMBL239359 | N-(5-(diethylamino)pentan-2-yl)-4-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.39E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197994((2S)-methyl 2-(4-(3-(3,5-dichlorophenyl)-1-(naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.84E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197986((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 4.74E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197997(4-(1-(3,5-bis(trifluoromethyl)phenyl)-3-(3,5-dichl...)copy SMILEScopy InChI
Affinity DataIC50: 6.48E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197987((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197990(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 9.33E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BJDPubMed
* indicates data uncertainty>20%