Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13052(3-quinolinecarbonitrile analog 22 | 4-[(2,4-Dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13047(3-quinolinecarbonitrile analog 10 | 4-[(2,4-Dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13051(3-quinolinecarbonitrile analog 21 | 4-[(2,4-Dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6114(3-quinolinecarbonitrile analog 2b | 4-[(2,4-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13045(3-quinolinecarbonitrile analog 5 | 4-[(2,4-Dichlor...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13053(3-quinolinecarbonitrile analog 23 | 4-[(2,4-Dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6112(3-quinolinecarbonitrile analog 2a | 4-[(2,4-dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMedDrugBank
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6493(3-quinolinecarbonitrile analog 2c | 4-Anilino-7-ph...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13046(3-quinolinecarbonitrile analog 7 | 4-[(2,4-Dichlor...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13049(3-quinolinecarbonitrile analog 17 | 4-[(2,4-Dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13048(3-quinolinecarbonitrile analog 15 | 4-[(2,4-Dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM13050(3-quinolinecarbonitrile analog 20 | 4-[(2,4-Dichlo...)copy SMILEScopy InChI
Affinity DataIC50: 84nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K779JPubMed
* indicates data uncertainty>20%