Compile Data Set for Download or QSAR

Found 5 hits of Enzyme Inhibition Constant Data   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM18370(N-(adamantan-1-yl)-5-[(3R,4R,5R)-3,4-dihydroxy-5-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765CMCPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM18369(N-(adamantan-1-yl)-4-[(3R,4R,5R)-3,4-dihydroxy-5-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765CMCPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM18371(N-(adamantan-1-yl)-6-[(3R,4R,5R)-3,4-dihydroxy-5-(...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+4nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765CMCPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM18368(2,5-anhydro-2,5-imino-D-glucitol based compound, 2...)copy SMILEScopy InChI
Affinity DataIC50: 3.93E+5nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765CMCPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM18367(2,5-anhydro-2,5-imino-D-glucitol based compound, 1...)copy SMILEScopy InChI
Affinity DataIC50: 5.07E+5nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765CMCPubMed
* indicates data uncertainty>20%