Compile Data Set for Download or QSAR

Found 39 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212534(1-(3-methoxyphenyl)-2-(phenylsulfonyl)ethanone | C...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212535(1-(4-methoxyphenyl)-2-(phenylsulfonyl)ethanone | C...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212525(1-(4-fluorophenyl)-2-(phenylsulfonyl)ethanone | CH...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212532(1-(3,4-dichlorophenyl)-2-(phenylsulfonyl)ethanone ...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212530(2-(phenylsulfonyl)-1-p-tolylethanone | CHEMBL39280...)copy SMILEScopy InChI
Affinity DataIC50: 102nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212529(2-(phenylsulfonyl)-1-(5-phenylthiophen-2-yl)ethano...)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212543(1-(5-(2,4-dichlorophenyl)furan-2-yl)-2-(phenylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 169nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)copy SMILEScopy InChI
Affinity DataIC50: 187nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212531(1-(4-chlorophenyl)-2-(phenylsulfonyl)ethanone | CH...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212533(2-(phenylsulfonyl)-1-(thiophen-3-yl)ethanone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 345nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212548(1-(3-methylbenzo[b]thiophen-2-yl)-2-(phenylsulfony...)copy SMILEScopy InChI
Affinity DataIC50: 525nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212547(1-(3,5-dimethylphenyl)-2-(phenylsulfonyl)ethanone ...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212551(1-(4-nitrophenyl)-2-(phenylsulfonyl)ethanone | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50117901(2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212538(1,1-diphenyl-3-(phenylsulfonyl)propan-2-one | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212544(1-(4-(diethylamino)phenyl)-2-(phenylsulfonyl)ethan...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212522(CHEMBL393285 | ethyl 3,3-dimethyl-4-oxo-5-(phenyls...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212524(CHEMBL241160 | N-benzyl-N-(phenylsulfonyl)benzamid...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212526(1-(2,5-dimethoxyphenyl)-2-(phenylsulfonyl)ethanone...)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212545(1-(phenylsulfonyl)butan-2-one | CHEMBL240761)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212536(1-phenyl-3-(phenylsulfonyl)propan-1-one | CHEMBL24...)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212549(1-(4-fluorophenyl)-3-(phenylsulfonyl)propan-1-one ...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212550(1-(4-chlorophenyl)-3-(phenylsulfonyl)propan-1-one ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212527(1-(4-bromophenyl)-3-(phenylsulfonyl)propan-1-one |...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212540(CHEMBL392809 | N-methyl-N-(phenylsulfonyl)benzamid...)copy SMILEScopy InChI
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212523(3,3-dimethyl-1-(phenylsulfonyl)butan-2-one | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212528(CHEMBL241150 | N-[(4-methylphenyl)sulfonyl]benzami...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212539(CHEMBL241149 | N-(phenylsulfonyl)benzamide)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212537(3-chloro-N-(phenylsulfonyl)benzamide | CHEMBL39197...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212546(CHEMBL391616 | N-(phenylsulfonyl)-4-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154511(CHEMBL189770 | N-(4-chlorophenylsulfonyl)benzamide...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212542(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50117901(2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212531(1-(4-chlorophenyl)-2-(phenylsulfonyl)ethanone | CH...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212530(2-(phenylsulfonyl)-1-p-tolylethanone | CHEMBL39280...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212525(1-(4-fluorophenyl)-2-(phenylsulfonyl)ethanone | CH...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212534(1-(3-methoxyphenyl)-2-(phenylsulfonyl)ethanone | C...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50212535(1-(4-methoxyphenyl)-2-(phenylsulfonyl)ethanone | C...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95CGPubMed
* indicates data uncertainty>20%