Compile Data Set for Download or QSAR

Found 34 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216434(CHEMBL245686 | dimethyl-(tetrahydro-pyran-4-yl)-{4...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216453(CHEMBL247537 | dimethyl-{4-[(E)-3-(4'-methyl-biphe...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216435(CHEMBL397647 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216442(CHEMBL393631 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216445(CHEMBL246520 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216431(CHEMBL246728 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216435(CHEMBL397647 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CCR2 receptor in PBMC assessed as inhibition of MCP1-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216435(CHEMBL397647 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at CCR2 receptor in THP1 cells assessed as inhibition of MCP1-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216432(CHEMBL394897 | N-(4-(7-chloro-2H-chromene-3-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216447(CHEMBL246933 | N-(4-(7-methyl-2H-chromene-3-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216446(CHEMBL264108 | N-(4-(7-bromo-2H-chromene-3-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216444(CHEMBL246313 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216455(CHEMBL248153 | N-(4-(3-chlorobenzamido)benzyl)-N,N...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216448(CHEMBL248151 | N-(4-(3-bromobenzamido)benzyl)-N,N-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216454(CHEMBL246522 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216452(CHEMBL245896 | N-(4-(3-chloro-4-fluorobenzamido)be...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216438(CHEMBL245696 | N-(4-(3,5-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216435(CHEMBL397647 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of MIP1alpha from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216428(CHEMBL393632 | N-(4-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216449(CHEMBL396571 | N-(4-(3-(3-fluorophenyl)acrylamido)...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216429(CHEMBL245497 | N-(4-(4-chlorobenzamido)benzyl)-N,N...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216437(CHEMBL397595 | N-(4-(3-(trifluoromethyl)benzamido)...)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216427(CHEMBL246725 | N-(4-(3-(3,4-dichlorophenyl)acrylam...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216440(CHEMBL436822 | N-(4-(3-cyanobenzamido)benzyl)-N,N-...)copy SMILEScopy InChI
Affinity DataIC50: 3.25E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216451(CHEMBL245290 | dimethyl-{4-[(4'-methyl-biphenyl-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.44E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216430(CHEMBL245289 | N-(4-(3-methylbenzamido)benzyl)-N,N...)copy SMILEScopy InChI
Affinity DataIC50: 4.25E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216441(CHEMBL247949 | N-(4-benzamidobenzyl)-N,N-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4.75E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216439(CHEMBL245694 | N-(4-(2,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216436(CHEMBL393835 | N-(4-((3,4-dichlorobenzamido)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 8.95E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216450(CHEMBL248358 | N-(4-(3-methoxybenzamido)benzyl)-N,...)copy SMILEScopy InChI
Affinity DataIC50: 9.55E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216443(CHEMBL245498 | N-(4-(2-chlorobenzamido)benzyl)-N,N...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216426(CHEMBL397646 | N-(4-(2,3-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216433(CHEMBL246729 | N-(4-(3,4-dichlorobenzamido)pheneth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216425(CHEMBL246104 | N-(3-(3,4-dichlorobenzamido)benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47NVRPubMed
* indicates data uncertainty>20%