Compile Data Set for Download or QSAR

Found 20 hits of Enzyme Inhibition Constant Data   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222490((R)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 131nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222490((R)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 147nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 191nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 259nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 291nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 327nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KdrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9PTZPubMed
* indicates data uncertainty>20%