Compile Data Set for Download or QSAR

Found 27 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198805(5-methyl-7-phenyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
TargeGen Inc.

Curated by ChEMBL
LigandPNGBDBM50198813(7-(2-chlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K3XPubMed
* indicates data uncertainty>20%