Compile Data Set for Download or QSAR

Found 29 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMedDrugBank
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271947(6-Methoxy-7-[2-(4-methylpiperazin-1-yl)-ethoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 9.23nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271896(6-Methyl-7-[3-(piperidin-1-yl)-propoxy]-4-(6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 15.4nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271839(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 75.9nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271897(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271948(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 133nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271840(6-Methyl-7-(3-morpholinopropoxy)-4-(benzothiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 172nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271900(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 178nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271899(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 186nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271841(6-Methyl-7-[3-(piperidin-1-yl)-propoxy]-4-(benzoth...)copy SMILEScopy InChI
Affinity DataIC50: 209nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271945(6-Methoxy-7-[2-(piperidin-1-yl)-ethoxyl]-4-(benzot...)copy SMILEScopy InChI
Affinity DataIC50: 371nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271842(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 646nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271946(6-Methoxy-7-(2-morpholinoethoxy)-4-(benzothiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271898(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271947(6-Methoxy-7-[2-(4-methylpiperazin-1-yl)-ethoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271842(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271898(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271897(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240843(2-Aminothiazole | Aminothiazole | Aminothiazoline ...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271948(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271839(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271946(6-Methoxy-7-(2-morpholinoethoxy)-4-(benzothiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271945(6-Methoxy-7-[2-(piperidin-1-yl)-ethoxyl]-4-(benzot...)copy SMILEScopy InChI
Affinity DataIC50: 4.48E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370459(CHEMBL443732)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271900(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 6.56E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271899(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271840(6-Methyl-7-(3-morpholinopropoxy)-4-(benzothiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271896(6-Methyl-7-[3-(piperidin-1-yl)-propoxy]-4-(6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 3.13E+5nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271841(6-Methyl-7-[3-(piperidin-1-yl)-propoxy]-4-(benzoth...)copy SMILEScopy InChI
Affinity DataIC50: 4.12E+5nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PZ6PubMed
* indicates data uncertainty>20%