Compile Data Set for Download or QSAR

Found 64 hits of Enzyme Inhibition Constant Data   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243699(2-(trifluoromethyl)-7-(2-(4-(2-(trifluoromethyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  0.550nMAssay Description:Binding affinity to human 5HT1D receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243700(4-(2-(4-(2-(trifluoromethyl)-1H-benzo[d]imidazol-4...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243699(2-(trifluoromethyl)-7-(2-(4-(2-(trifluoromethyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243699(2-(trifluoromethyl)-7-(2-(4-(2-(trifluoromethyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Binding affinity to human 5HT1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244213(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244213(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243853(4-(3-(4-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244213(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244212(5-((4-(2-(4-tert-Butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244175(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244212(5-((4-(2-(4-tert-Butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244213(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 17.5nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244212(5-((4-(2-(4-tert-Butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244211(6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244212(5-((4-(2-(4-tert-Butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244133(2-(4-tert-Butylphenyl)-4-(4-(2-(2-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244213(5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244175(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244132(2-(4-Isopropylphenyl)-4-(4-(2-(2-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244090(4-(2-(4-(2-(4-Ethylphenyl)-1H-benzo[d]imidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244089(2-(4-Ethylphenyl)-4-(4-(2-(2-(trifluoromethyl)-1Hb...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244132(2-(4-Isopropylphenyl)-4-(4-(2-(2-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243900(4-((4-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244090(4-(2-(4-(2-(4-Ethylphenyl)-1H-benzo[d]imidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244175(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244133(2-(4-tert-Butylphenyl)-4-(4-(2-(2-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243700(4-(2-(4-(2-(trifluoromethyl)-1H-benzo[d]imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244132(2-(4-Isopropylphenyl)-4-(4-(2-(2-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244134(4-(2-(4-(2-(2,4-Dimethylphenyl)-1H-benzo[d]imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244133(2-(4-tert-Butylphenyl)-4-(4-(2-(2-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244088(2-p-Tolyl-4-(4-(2-(2-(trifluoromethyl)-1Hbenzo[d]i...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244175(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243699(2-(trifluoromethyl)-7-(2-(4-(2-(trifluoromethyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244089(2-(4-Ethylphenyl)-4-(4-(2-(2-(trifluoromethyl)-1Hb...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244088(2-p-Tolyl-4-(4-(2-(2-(trifluoromethyl)-1Hbenzo[d]i...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243853(4-(3-(4-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243900(4-((4-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244090(4-(2-(4-(2-(4-Ethylphenyl)-1H-benzo[d]imidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243700(4-(2-(4-(2-(trifluoromethyl)-1H-benzo[d]imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
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